Profhilo

Hyaluronic acid fillers are typically stabilised by crosslinking with 1,4-butanediol diglycidyl ether (BDDE), to confer longevity. Otherwise, they would break down and eliminate within a week or two of injection.

The science behind Profhilo is fascinating. Prof. Chiara Schiraldi and Prof. Mario de Rosa developed the technology at the Second University of Naples. It is the first stabilised hyaluronic acid based product without the use of chemical cross-linking agents (BDDE). During the process, low and high molecular weight hyaluronic acid bond together using a patented completely chemical-free, thermal process that confers structural and rheologic stability.

Profhilo is available in one formulation – 64mg of hyaluronic acid in a 2ml pre-filled syringe (32mg of high molecular weight hyaluronic acid + 32mg of low molecular weight hyaluronic acid).

Owing to this new technology it was possible to combine 32mg of low molecular weight hyaluronic acid (80 – 100 KDa) and 32mg of high molecular weight hyaluronic acid (1100 – 1400 KDa) while maintaining complete manageability. It results in a total concentration of 64mg of hyaluronic acid which has never been achieved before precisely because of technological limitations. This process does not involve the use of chemical cross-linking agents and the final product, Profhilo, is pure hyaluronic acid. The formulation of hyaluronic acid with different molecular weights contained in Profhilo means that it has a Hydrolift® Action and makes it easy to inject. Studies of Profhilo have also shown significant up-regulation of collagen and elastin production. These are an outcome by both fibroblasts and keratinocytes resulting in minimal tissue inflammation.

Dr Tailor delivers the treatment to the face using the 5-point BAP (Bio Aesthetic Points) technique, the optimum method for placement of the product. We use the 5 injection points on each side of the face, away from major vessels, nerves etc. in such a way as to maximise the ‘spreadability’ of the product through diffuse regions of the cheek and jawline.

The product flows and distributes itself evenly. Moreover, it is integrating within your skin’s tissue without resistance (rather than remaining at the same place). Therefore, this makes it naturally a much less painful procedure than dermal fillers.

Profhilo won’t produce lumps and bumps in these or other areas. Even if we inject it as a bolus, it flows freely into the tissue and moves completely naturally and fills them evenly within 24 to 48 hours. Profhilo’s unsurpassed level of tissue integration and biocompatibility is due to its unique manufacturing process.

While most dermal fillers contain local anaesthetic such as lidocaine to assist in a pain-free procedure, we do not need to use any for Profhilo injections. We also us a minute needle which means that the skin is generally free from marks and bruises.

We recommend an initial treatment plan of 2-3 treatments every 1 month followed by maintenance every 3 to 4 months.

It’s important to note that Profhilo is an excellent option for the earlier prevention of lines, wrinkles, and loss of volume. Beyond the teens, due to genetic or intrinsic ageing, we lose collagen and elastin from the dermis. This results in our skin becoming thinner and less elastic.

The needle for Profhilo is extremely small meaning the skin is generally free from marks and bruises, as long as pre-treatment advice is followed. There tends to be no pain with Profhilo, although it can be mildly uncomfortable.

Transient redness, pain, itching, discolouration or tenderness at the implant site.

Hyaluronic acid completely brakes down within the skin leaving no trace.

Individuals with a known hypersensitivity to hyaluronic acid. Also, pregnant ladies and women who breastfeed.